In addition to our experienced interdisciplinary team, Extruded Pharmaceuticals Ltd works closely with a wide array of organisations. For instance, our excellent relationship with clinicians at Queens Hospital, Birmingham, has been crucial to the success of our projects to date. Please get in touch today for a preliminary and confidential discussion about pharmaceutical manufacturing.
University of Birmingham
Our company has worked on cancer treatments with the University of Birmingham, from formulation development and scale-up to technology transfer and cGMP manufacture of implantable devices.
Hot-Melt Extrusion Development
We are also working with a UK-based pharmaceutical company, developing a hot-melt extrusion process to manufacture a long-acting subdermal polymeric implant. Extruded Pharmaceuticals Ltd designed the protocol to take the product from assay and related substance method development and validation through pre-formulation, formulation development, and preclinical testing, moving onto scale-up, technology transfer and cGMP manufacture of a clinical batch.
The above projects entailed contract negotiations with raw material suppliers, a contract research organisation to perform the preclinical testing, and a contract manufacturer for the final clinical batch production.
Additionally, Extruded Pharmaceuticals Ltd undertook discussions with the MHRA about the pharmacology and toxicology data required for submission of the Clinical Trial Authorisation application. We wish to collaborate with pharmaceutical companies to determine if the EPL Low Temperature, Low Shear Extrusion platform (LTLE) is suitable for these products.
Working closely with various organisations, we specialise in pharmaceutical manufacturing.